Simvastatin Solid Dispersion Prepared by Microwave Fusion Technique - Paperback
$85.37
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Simvastatin Solid Dispersion Prepared by Microwave Fusion Technique - Paperback
$85.37
by Chaudhary Haresh (Author), Patel B. N. (Author), Patel D. M. (Author)
Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-free solid dispersions and to enhance the solubility and dissolution rate of simvastatin by a solid dispersion.
Number of Pages: 124
Dimensions: 0.29 x 9 x 6 IN
Publication Date: February 13, 2014
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